Definition of collagen and its role in the human body
Collagen is the main protein in the skin, representing 80 to 85% of the dry weight of the dermis. This large, fibrous protein is a polysaccharide, a natural carbohydrate of the glycosaminoglycan family. Collagen is an almost complete protein, made up of 19 essential amino acids. Collagen is characterised by the regular repetition on the 3 alpha chains of the amino acid triplets Glycine - X - Y (where X and Y are other amino acids, most often X = proline and Y = hydroxyproline), the most common of which is the sequence Glycine-Proline-Hydroxyproline. These helices join together to form the collagen fibres that form the basis of the extra-cellular matrix.
We talk about collagen, but it would be more accurate to talk about collagens. Today we know 28 of them, 12 of which are expressed in the skin. Depending on their structure, size and role, these different collagens perform different functions in the body and are classified into several types. The most abundant in the human body are collagen types 1, 2, 3 and 4.
Collagen forms the basis of our connective tissues such as bones, skin, tendons and cartilage. Collagens play an essential role in cell adhesion and communication between keratinocytes and in the general cohesion of the epidermis.
It is collagen that gives the skin its cohesion, resistance, firmness and smoothness.
Hyaluronic acid, collagen, elastin and proteoglycans form an assembly that constitutes the support tissue of the skin and many other tissues.
The rise in popularity of collagen supplements for health and aesthetics
Collagen has had a strong presence in the world of cosmetics for many years. Now, spurred on by new clinical studies, collagen food supplements are taking centre stage for their proven effectiveness in improving the appearance of the skin.
Taking collagen in food supplement form helps to compensate in part for the natural decline in our stocks of natural collagen and to support the natural ageing process. By starting to take collagen from the age of 30, this supplementation can help the skin to age well and delay or reduce the appearance of wrinkles.
How does collagen work? Ingested as a food supplement, collagen peptides circulate in the bloodstream and reach the tissues, making the skin denser and more resistant.












