Aroma-Zone Polyglutamic Acid Active Ingredient

INCI Name: Sodium polyglutamate

VEGAN

BIOCHEMICAL COMPOSITION

Polyglutamic acid is composed of D-glutamic acid and L-glutamic acid. High-molecular-weight polyglutamic acid (approximately 2000 kDa) forms a protective barrier on the skin’s surface, while low-molecular-weight polyglutamic acid (approximately 1 kDa) penetrates the skin to act at a deeper level.

SUSTAINABILITY & TRACEABILITY

100% natural origin, the polyglutamic acid used by Aroma-Zone is produced through non-GMO fermentation.

Polyglutamic acid is a polypeptide (a chain of amino acids) naturally found in fermented soybeans, known as natto. Its strong affinity for water molecules and its ability to stimulate the skin’s natural hydration factor give it intense moisturizing properties. This polymer has an exceptional ability to retain water, estimated at 5,000 times its weight, making it even more effective than hyaluronic acid in terms of skin hydration. PGA acts like a sponge, forming a protective film on the skin’s surface that “swells” upon contact with water. It therefore effectively hydrates the epidermis while limiting transepidermal water loss (TEWL). This molecule is not naturally present in the body, but it preserves the hyaluronic acid naturally present in our skin and stimulates collagen production.

Tests* conducted on a human skin model have demonstrated polyglutamic acid’s ability to strengthen the skin barrier and to boost hyaluronic acid levels in cells.

A Note from Adeline Nalin, Head Pharmacist and Toxicologist at Aroma-Zone

“An in vitro study on a reconstituted skin model using γ-PGA (high molecular weight) showed that it stimulates skin barrier markers (filaggrin, loricrin, involucrin, etc.) in keratinocytes, and increases the expression of aquaporin 3 (linked to hydration) and hyaluronic acid synthesis [Hyun-Ju Ko et al, Poly-γ-Glutamic Acid from a Novel Bacillus subtilis Strain: Strengthening the Skin Barrier and Improving Moisture Retention in Keratinocytes and a Reconstructed Skin Model, Int J Mol Sci, 2025 Jan 24;26(3):983]. This suggests not only good tolerability but also a beneficial effect on the barrier and hydration. Some skin irritation is always possible in the most sensitive skin types; however, our Hyaluronic Acid & Polyglutamic Acid Cream demonstrates excellent skin tolerance results, including on sensitive skin.”

Adeline Nalin - Head Pharmacist and Toxicologist

A Note from Our Aroma-Zone Toxicologist

“The high molecular weight of the polyglutamic acid used by Aroma-Zone limits its penetration into the deeper layers of the skin, which explains its high tolerance. Some skin irritation is always possible in the most sensitive skin types; however, our Hyaluronic Acid & Polyglutamic Acid Cream demonstrates excellent skin tolerance results, including on sensitive skin.”

Adeline Nalin - Head Pharmacist and Toxicologist

A Note from the Dermatologist

“Polyglutamic acid can hold up to 5,000 times its weight in water, making it an excellent ally for intensely hydrating the skin and strengthening the skin barrier. I therefore recommend it primarily for dry, dehydrated, or irritated skin. It can be used in the morning and/or evening, alone or in combination with other active ingredients, for example after a vitamin C-based serum or after applying an exfoliant.”

Dr. Dima Haidar - Dermatologist

Polyglutamic acid is gaining significant traction thanks to its exceptional moisturising power: like hyaluronic acid, it retains water, but up to 5,000 times its weight, with comparable molecular weights. In formulations, it provides intense and long-lasting hydration, but also stands out because it counteracts the enzyme that breaks down hyaluronic acid (hyaluronidase, naturally present in our skin). It thus helps preserve the skin's natural hyaluronic acid reserves while enhancing the plumping effect of moisturisers.

All skin types, dehydrated skin, first signs of ageing, mature skin.

Dehydration, loss of firmness and elasticity, wrinkles and fine lines.

• Intensely hydrates the skin

• Reduces wrinkles and fine lines

• Firms the facial contours

• Improves skin elasticity.

Hyaluronic Acid & Polyglutamic Acid Cream

To enjoy the benefits of polyglutamic acid, discover our Hyaluronic Acid & Polyglutamic Acid Cream. Its formula hydrates the skin for 48 hours and leaves it feeling baby-soft, supple and plump thanks to this moisturising face cream that combines next-generation hyaluronic acid and polyglutamic acid. The essential duo to boost your hydration.

I'm Delphine Duc, a biological engineer specialising in cosmetology, and I've been passionate about the field of cosmetics for almost 10 years. I started making my own homemade cosmetics using Aroma Zone products to tackle my skin problems. Eventually, I decided to train as a cosmetologist and ultimately to create a bespoke cosmetics brand to address everyone’s individual skin concerns.