Everything therefore suggests that cellulite requires a holistic approach to be properly managed. This holistic perspective is precisely what functional medicine, which is holistic by nature, addresses. Our expert’s insight below illustrates just how cellulite, far from fitting the simplistic models sometimes attributed to it, is based on multiple and complex interactions.
A word from the functional medicine doctor
"I see many cases in my practice (lipoedema), yet cellulite is multifactorial. It is often linked to a metabolic problem: either it reflects low-grade inflammation (too many pro-inflammatory fats versus omega-3s), or it results from poor lymphatic circulation linked to thyroid dysfunction, or it stems from insulin resistance: breakfasts that are too sugary, snacks that are too sugary… There is also a link with cortisol: if pregnenolone, a precursor to many hormones, is mobilised to produce cortisol in response to stress, other hormonal pathways are less effectively supported (such as that of testosterone), which can contribute to cellulite. Finally, a lack of physical activity also plays an important role."
Dr Yoni Assouly, functional medicine doctor and author
A word from the nutritionist
"What role do blood sugar levels and insulin play in the development or persistence of cellulite? Insulin is a hormone that stimulates the storage of lipids in fat cells and inhibits the breakdown of fat (lipolysis). Chronic hyperinsulinaemia therefore promotes the hypertrophy of fat cells, the accumulation of subcutaneous fat and the structural changes in adipose tissue characteristic of cellulite. Repeated blood glucose spikes and insulin resistance are also associated with increased oxidative stress and low-grade chronic inflammation. Indeed, the inflammatory component of cellulite is now well established. Added to this are effects on microcirculation and water retention, which can accentuate the ‘orange peel’ appearance. Several hypotheses* link alterations associated with metabolic syndrome (characterised in particular by insulin resistance, abdominal obesity, dyslipidaemia, etc.) to the signs of cellulite. These two conditions share common mechanisms, such as inflammation, hormonal imbalances and disturbances in the functioning of adipose tissue."
Reference: Adamidis N, Papalexis P, Adamidis S. Exploring the Link Between Metabolic Syndrome and Cellulite. Cureus. 29 June 2024;16(6):e63464. doi: 10.7759/cureus.63464.
Lila Bouber, PhD in Nutrition and Scientific Consultant