A quick reminder to start with: a sore throat is an inflammation of the tonsils. These are two tissue glands located on either side at the back of the throat. They are lymph nodes that play a major role in immunity. The tonsils are there to trap bacteria or viruses that might enter our body through the throat. They act as a first line of defence by producing antibodies and activating immune cells. This protective function explains why they are often the first to be affected during respiratory infections. There are two types of sore throats: those caused by viruses and those caused by bacteria.
Viral sore throats account for about 80% of cases in adults and are caused by various viruses such as adenovirus, Epstein-Barr virus, or rhinovirus. Bacterial sore throats, on the other hand, are mainly caused by Group A streptococcus. This distinction is crucial, as it entirely determines the course of treatment.
A sore throat is considered prolonged if it lasts longer than 10 days. That is, it persists despite the initiation of appropriate treatment. This contrasts with a typical sore throat, which improves within a few days and most often does not require antibiotics when viral in origin.
It is worth noting that viral tonsillitis resolves spontaneously within 3 to 5 days, up to 7 days at most. In contrast, bacterial tonsillitis treated with a specific antibiotic shows improvement within 24 to 48 hours after treatment begins and resolves within 5 to 7 days. This improvement is generally marked by a decrease in fever, reduced pain when swallowing, and a gradual return of appetite.
If symptoms persist beyond 10 days, this is outside the norm. This is one of the signs that should prompt you to see your doctor again promptly. This applies whether you have white strep throat or red strep throat that lasts more than 10 days. This unusual duration may mask complications or reveal an underlying cause that requires further investigation.
Several mechanisms can explain this abnormal duration:
Inflammation: it refuses to subside in the tonsils. Normally, after a few days, the inflammatory process gradually subsides. If it persists, it is a sign that an external factor is fueling this inflammation. This chronic inflammation can be fueled by irritants such as tobacco, pollution, acid reflux from the stomach, or allergens present in the environment. The body then continues to produce inflammatory mediators that maintain the symptoms.
The microbiome: The mouth and throat are rich in microorganisms known as oral flora. Typically, good and bad bacteria coexist, which helps maintain good health. However, a prolonged infection can disrupt this balance and lead to an overgrowth of harmful bacteria. This imbalance, known as dysbiosis, can be exacerbated by the use of broad-spectrum antibiotics, which also eliminate the beneficial, protective bacteria. It can then take several weeks for this ecosystem to regain its natural balance.










