An allergy is an excessive and inappropriate reaction by the immune system to a normally harmless substance. Thinking the body is in danger, it sets up a defence strategy and releases antibodies and the histamines responsible for allergic reactions which include skin reactions, breathing difficulties, swollen eyes, etc.
An allergy to dogs is in fact a reaction to allergens carried by dogs. These may be molecules contained in their saliva, urine or skin. These molecules generally enter the body via the respiratory tract.
There may be multiple exposures to these allergens before the allergy develops. This is known as the "sensitisation" phase and can last for months or even years.
During this period, certain allergen molecules are stored by the body so that the immune system can prepare its defences. When an allergy occurs, the mast cells responsible for protecting the body release histamine, which reacts to the perceived threat with a localised inflammatory response which varies in severity.

