Cheilitis refers to inflammation of the lips. It can affect the vermilion border – that is, the visible red part of the lips – the lip margins or the skin around the mouth. When it is of the eczematous type, it is referred to as eczematous cheilitis or lip dermatitis [1]. It most commonly presents as dryness, redness, flaking, cracks, itching or a sensation of irritation. The lips may become sensitive, uncomfortable and sometimes painful when the skin cracks. Cheilitis may be linked to an atopic predisposition, local irritation or a contact allergy. It can also be confused with other lip conditions, notably a fungal infection of the corners of the mouth, perioral dermatitis or cold sores. This clinical similarity highlights the importance of seeking medical advice if the symptoms persist [1,2,3].
What are the different types?
Here are the different types:
Irritant cheilitis: Caused by repeated contact with irritants, such as saliva, certain toothpastes, acidic or spicy foods, cold, wind or repeated rubbing [1,4]
Lip-licking dermatitis: Occurs when the lips are repeatedly licked. Saliva first moistens and then dries out the skin, which perpetuates redness, cracks and tightness, particularly in children [4]
Allergic contact cheilitis: An allergic reaction triggered by a substance coming into contact with the lips or the area around them. Cosmetics, lipsticks, lip balms, perfumes, preservatives, toothpastes or certain professional products may be involved [2,5]
Atopic cheilitis: Occurs in the context of atopic dermatitis. In this case, other areas of the body are also likely to develop similar symptoms, such as dryness, redness, itching or patches of eczema in skin folds, on the eyelids, hands or other areas of the skin [6,7,8]
Angular cheilitis or perleche: Affects the commissures, i.e. the corners of the mouth. It is not always eczematous: it can be triggered by local moisture, a Candida infection, bacteria, dental braces, irritation or certain local vulnerabilities [9,10].










