A stomach ulcer (or gastric ulcer) is an open sore that develops in the lining of the stomach. An ulcer is generally defined as a break in the stomach lining measuring at least 5 mm in diameter. It occurs when the stomach's protective lining is no longer able to withstand the highly acidic and digestive effects of gastric juices. Ulcers of the duodenum and the distal prepyloric region of the stomach are associated with increased stomach acid production. In contrast, people with gastric ulcers usually have normal or even reduced acid secretion. In these cases, the ulcer is thought to result primarily from a weakened or damaged protective lining rather than excess acid.
Stomach ulcers rarely develop near the entrance of the stomach but are more commonly found along the lesser curvature, closer to the stomach's outlet. They often begin with irritation of the stomach lining, causing mild discomfort that may go unnoticed. As the condition progresses, a characteristic symptom may appear: hunger-like pain that occurs on an empty stomach and is temporarily relieved by eating. This happens because food briefly buffers stomach acid, reducing its direct contact with the damaged lining. Once digestion resumes, the acid can once again irritate the unprotected tissue, causing the pain to return. Normally, the stomach's protective mechanisms prevent it from digesting itself, but when the lining is damaged, these natural defences become less effective.





