Within muscle cells, calcium is contained in an isolated compartment (endoplasmic reticulum). Muscle contraction is triggered by the release of calcium from this compartment. Spilanthol activates receptors in muscle cells that prevent the release of calcium (CB1 receptors). As a result, a reversible relaxation of the muscle is observed.
The Spilanthes Active Ingredient
FIRMING ANTI-AGING SMOOTHING
If further proof were needed of the power of plant-based active ingredients, Spilanthes would be a textbook example. The plant-derived molecule spilanthol provides rapid muscle-relaxing activity (muscle relaxation) that inhibits contractions of the facial subcutaneous muscles, which cause expression lines. Result: visible action on wrinkles from the very first applications and an instant anti-fatigue effect, for smoother skin.


Rich Vegan Collagen & Spilanthes Cream
The Rich Vegan Collagen & Spilanthes Cream is a treatment designed for mature, dry to very dry skin, including sensitive skin. Its formula combines biomimetic vegan collagen, Spilanthes extract, and hyaluronic acid to comprehensively address visible signs of aging. Spilanthes, rich in spilanthol, targets expression lines thanks to its relaxing effect on skin micro-contractions, while vegan collagen helps improve firmness, density, and the definition of the facial contour. Hyaluronic acid completes this synergy by supporting hydration and a plump appearance of the skin. Used morning and night on the face and neck after serum, this cream helps smooth the skin, strengthen its structure, and improve its comfort, with a rich, creamy texture that absorbs quickly without leaving a greasy film.

Why does Spilanthol have a muscle-relaxing effect?

Why does Spilanthol have a muscle-relaxing effect?
Why does Spilanthol have a muscle-relaxing effect?

What other natural product can have muscle-relaxing effects?

What other natural product can have muscle-relaxing effects?
What other natural product can have muscle-relaxing effects?
Butterfly lavender extract, rich in fenchone, also has muscle-relaxing effects on subcutaneous micro-contractions. It is combined with Spilanthol in an innovative plant-based complex within the Spilanthes Plant Concentrated Serum.
Article written by Morgane CARRARA, our phytochemistry expert

Morgane earned her Ph.D. in 2022; Morgane is a researcher specializing in phytochemistry. Passionate about natural substances, she dedicates her research to studying the composition and properties of plant extracts.
Bibliography
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2
Kowalczyk, S.; Grymel, M.; Bilik, J.; Kula, W.; Wawoczny, A.; Grymel, P.; Gillner, D. Selected Plants as Sources of Natural and Active Ingredients for Cosmetics of the Future. Applied Sciences 2024, 14 (8), 3487.
https://doi.org/10.3390/app14083487
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Savic, S. M.; Cekic, N. D.; Savic, S. R.; Ilic, T. M.; Savic, S. D. ‘All-Natural’ Anti-Wrinkle Emulsion Serum with Acmella Oleracea Extract: A Design of Experiments (DoE) Formulation Approach, Rheology and in Vivo Skin Performance/Efficacy Evaluation. International Journal of Cosmetic Science 2021, 43 (5), 530–546.
https://doi.org/10.1111/ics.12726





