Liposomal Vitamin C: Benefits and Uses?

What is a liposomal form?

Liposomal vitamin C utilises an innovative encapsulation method. It is, in fact, vitamin C protected by a phospholipid envelope. This artificial entity (active ingredient at the centre + concentric bilayers of excipients) is called a ‘liposome’. It is microscopic in size: its diameter is measured in nanometres (generally less than 300 nm for optimal absorption).

phospholipids belong to the family of fats. These are specialised lipids, consisting of a hydrophilic head (i.e. one that binds to water) and two lipophilic tails (i.e. ones that bind to fats). They are involved in numerous physiological processes within our bodies and are all the more interesting because they are difficult to find in our diet.

In the case of liposomal vitamin C supplements, the main component is phosphatidylcholine – the most abundant phospholipid in our intestinal mucus. It is sometimes of plant origin (in the form of lecithin extracted from sunflowers or soya, for example).

What is the difference between conventional vitamin C and liposomal vitamin C?

 In traditional dietary supplements, vitamin C is present in its ‘simple’ form, that is to say, in a water-soluble form. This means that it is soluble only in water. In contrast, liposomal vitamin C, thanks to its lipid barrier, is fat-soluble.

 This distinctive feature enables it to act within our bodies by engaging other metabolic processes than standard vitamin C. Its bioavailability, mechanisms of action and distribution, as well as its potential for elimination, are different – and this is precisely what makes it so valuable.

Benefits similar to those of standard ascorbic acid

Whether with or without phospholipid layers, we are still talking about the same active ingredient: vitamin C (ascorbic acid, or even sodium ascorbate). It is this substance alone that gives its potential beauty and wellbeing properties to your dietary supplement. Conventional vitamin C and its liposomal form are therefore thought to offer identical benefits. In particular, both could help you to:

• Reduce feelings of tiredness (particularly during seasonal changes);

• Protect your cells against oxidative stress caused by free radicals;

• Support the normal functioning of your immune system;

• Support the normal functioning of your nervous system;

• Maintain normal energy metabolism;

• Contribute to the normal formation of collagen (for your skin, your bones, cartilage, teeth, gums and blood vessels);

• Support the normal functions of your body during and after intense physical exercise.

Optimal absorption

Liposomes have been known since the 1960s and have therefore had ample time to be studied. It is now established that they offer better absorption in the gut, greater stability and higher bioavailability for the body. For these same reasons, liposomal forms may also be easier to tolerate in cases of a sensitive gut (1).

 More specifically, what about our tiny vesicles [vitamin C + phospholipids]? This is a fairly innovative form which, in fact, does not yet have a wealth of scientific studies to its credit. One landmark publication stands out, however: that by Janelle Davis and her team (United States), published in 2016 (2). Following their tests, the researchers concluded that taking liposomal vitamin C orally was associated with a higher blood concentration of vitamin C than that of non-encapsulated vitamin C. In other words: its bioavailability appears to be better.

Optimised Vitamin C powder

Vitamin C powder formulated with PureWay-C®, combining plant-based lipids and citrus bioflavonoids for optimal absorption and good digestive tolerance. Ideal as a course of treatment to boost immunity, reduce fatigue, stimulate collagen synthesis and combat oxidative stress. Supplied with a measuring spoon, it dissolves easily in a glass of water, juice or a protein shake for athletes.

Discover Optimised Vitamin C Powder – 150 g – Food supplement

Does liposomal vitamin C have any side effects or contraindications?

Generally speaking, high doses of ascorbic acid can cause diarrhoea, nausea, bloating and headaches. You should therefore ensure you follow the recommended dosages stated on the packaging of your dietary supplement.

It should also be noted that liposomal ascorbic acid, which is hydrophobic by nature, cannot be eliminated in the same way as conventional vitamin C (i.e. via the kidneys and, ultimately, in the urine). The consequences of a possible overdose may therefore differ.

When and how should it be taken as a dietary supplement?

On the dietary supplement market, you can find vitamin C encapsulated in the form of powder to be dissolved, capsules to be swallowed or liquid to be drunk. Its form is therefore very similar to that of the traditional version: in that respect, you’ll feel right at home! It’s up to you to choose the formulation that best suits your tastes, preferences and lifestyle.

The method of intake varies depending on the concentration and form of the food supplements. It is therefore difficult to draw any general rules, although it is generally recommended to take supplements with a meal to encourage the release of the liposomes. It is best to refer to the instructions for use for the product you have chosen.

For your information, the recommended daily intake (ANSES) of vitamin C is 110 mg for an average adult (aged 13 and over). This figure may vary depending on various factors, including your state of health (pregnancy, smoking, etc.).

Hélène Betoux is a French beauty journalist specialising in web media. Every day she writes tips, advice, and guides to help consumers choose the right beauty products. With a strong interest in natural, organic, and clean cosmetics, she analyses and shares trends and innovations in the sector.