The key role of the skin microbiome
The skin is home to a skin microbiome, that is, a collection of microorganisms (bacteria, yeasts, etc.) that contribute to its balance and barrier function. Among these, Cutibacterium acnes is often associated with the symptoms of acne. However, contrary to popular belief, this bacterium is not necessarily problematic: certain strains help maintain healthy skin by regulating the pH and limiting the proliferation of undesirable microorganisms. Research by Dessinioti & Katsambas (2020) and Dagnelie et al. (2021) show that it is not the presence of C. acnes in itself that promotes blemishes, but an imbalance in the skin microbiome, known as cutaneous dysbiosis (1, 2). In forms of inflammatory acne, there is indeed an overabundance of certain pro-inflammatory strains, as well as the formation of biofilms, which make the bacteria more resistant and perpetuate local inflammation (4).









